Is “The Pill” Safe?

ORTHO TRI-CYCLEN Tablets
ORTHO-CYCLEN Tablets
Commonly know as the oral contraceptive “The Pill”

ADVERSE REACTION
ORTHO TRI-CYCLEN Tablets
ORTHO-CYCLEN Tablets

An Increased risk of the following serious adverse reaction has been associated with the use of oral contraceptives (ORTHO TRI-CYCLEN Tablets, ORTHO-CYCLEN Tablets):

• Thrombophlebitis and venous thrombosis with or without embolism
• Arterial Thromboembolism
• Pulmonary embolism
• Myocardial infarction
• Cerebral hemorrhage
• Cerebral thrombosis
• Hypertension
• Gallbladder Disease
• Hepatic Adenoma or benign liver tumors

The Following adverse reaction have been reported in patients receiving oral contraceptives and are believed to be drug-related (ORTHO TRI-CYCLEN Tablets, ORTHO-CYCLEN Tablets):

• Nausea
• Vomiting
• Gastrointestinal symptoms (such as abdominal cramps and bloating)
• Breakthrough bleeding
• spotting
• Change in menstrual flow
• Amenorhea (cessation of the menstrual cycle)
• Temporary infertility after discontinuation of treatment
• Edema
• Melasma which may persist
• Breast changes: tenderness, enlargement,
• Change in weight (increase or decrease)
• Change in cervical erosion and secretion
• Diminution in lactation when given immediately postpartum
• Cholestatic jaundice
• Migraine
• Rash (allergic)
• Mental depression
• Reduced tolerance to
• Vaginal Candidiasis
• Change in corneal curvature (steepening)
• Intolerance to contact lenses

The following adverse reaction have been reported in user of oral contraceptives and the association has been neither confirmed nor refuted (ORTHO TRI-CYCLEN Tablets, ORTHO-CYCLEN Tablets)

• Pre-menstrual syndrome
• Cataracts
• Changes in appetite
• Cystitis-like syndrome
• Headache
• Nervousness
• Dizziness
• Hirsutism
• Loss of Scalp hair
• Erythema Muliforme
• Erythema nodosum
• Hermorhagic eruption
• Vaginitis
• Porphyria
• Impaired renal function
• Hemolytic Uremic Syndrome
• Acne
• Changes in libido
• Colitis
• Budd-Chiari Syndrome